England fast bowler James Anderson has been ruled out of the final two Tests of the four-match series against South Africa due to a rib injury as the “cursed” tour claimed another victim.

Anderson sustained a rib injury in England's 189-run win in the second Test at Newlands and underwent an MRI scan in Cape Town.

It is the latest in a number of setbacks for England who despite the mishaps levelled the series with a thrilling victory Tuesday.

Opener Rory Burns underwent surgery in London this week after he injured his ankle in a football kickabout on the eve of the second Test.

Jofra Archer also missed the Cape Town match because of an elbow injury, although scans have since cleared him to play in the rest of the tour.

About 10 players and more support staff were laid low by a mystery virus that swept through the squad before the first Test in Pretoria.

England all-rounder Ben Stokes has labelled the tour as “cursed”. 

His father suffered a stroke days after arriving in the country to watch his son and remains in hospital in Johannesburg.

Anderson, England's leading Test wicket-taker, returned to the side following a lengthy layoff due to a calf injury last year, claiming five wickets in the first innings at Cape Town and two in the second before pulling up injured.

The third and penultimate Test begins in Port Elizabeth on Jan. 16.